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Gonadotropin: Uses for Fertility, Evidence-Based Dosing, Risks, and Side Effects

Gonadotropins are prescription hormones that directly stimulate the ovaries and testes. In women, follicle-stimulating hormone (FSH) and luteinizing hormone (LH) drive follicle growth and ovulation. In men, human chorionic gonadotropin (hCG) acts like LH to raise intratesticular testosterone, and FSH supports Sertoli cells for sperm production. Clinically, gonadotropins are used to induce ovulation in anovulatory cycles, optimize oocyte yield...

Gondoic acid: What It Is, Proven Benefits, How to Use, Dosage, and Side Effects

Gondoic acid—also called cis-11-eicosenoic acid or 20:1 (n-9)—is a long-chain, omega-9 monounsaturated fatty acid. It occurs naturally in certain plant oils and nuts, with particularly high levels in jojoba (a “liquid wax” widely used in cosmetics) and trace-to-low levels in edible seed oils such as rapeseed/canola. Interest in gondoic acid has grown because long-chain omega-9 fats can influence cell...

Gongronema latifolium: Evidence-Based Benefits, Preparation Methods, Dosage Guidelines, and Side Effects

Gongronema latifolium is a leafy vine native to West and Central Africa, best known by names like “utazi” (Igbo) and “arokeke” (Yoruba). In kitchens, its pleasantly bitter leaves season soups and stews; in traditional medicine, the plant is used for blood sugar control, digestive comfort, and general vitality. Modern lab and animal research points to antioxidant, anti-inflammatory, lipid-lowering, and...

Goshajinkigan: Chemotherapy-Induced Neuropathy Support, Benefits, Dosage, and Risks

Goshajinkigan (pronounced go-sha-jin-kee-gahn), often shortened to GJG, is a classic Kampo (Japanese traditional) herbal formula used to ease nerve-related symptoms such as numbness, tingling, cold sensitivity, and muscle cramps. Modern research has explored GJG most in two areas: diabetic nerve complications and chemotherapy-induced peripheral neuropathy (CIPN). The formula blends ten botanicals—including rehmannia, cinnamon bark, poria, and processed aconite root—aimed...

Gossypol: Investigational Uses in Men’s Health and Oncology, Trial Doses, and Adverse Effects

Gossypol is a naturally occurring polyphenolic compound found in the cotton plant. It has a complex history: once tested as a nonhormonal male contraceptive, later explored as an anticancer agent, and long recognized as a toxin in animal feeds when cottonseed products are not properly processed. That mix of promise and risk makes gossypol unusual. Its potential benefits—temporary suppression...

Goutweed (Aegopodium podagraria) health benefits, how to use it, dosage, and side effects

Goutweed (Aegopodium podagraria), also called ground elder or herb gerard, is a vigorous leafy herb in the carrot family that has been eaten and used in folk medicine across Europe for centuries. Today, interest is rising again because its young leaves are rich in polyphenols and other phytochemicals with antioxidant and anti-inflammatory activity. Early laboratory and animal research suggests...

Graminex pollen extract: Uses for Urinary Incontinence and Prostate Symptoms, Dosage Ranges, and Safety Considerations

Graminex® flower pollen extract is a standardized blend of water-soluble and lipid-soluble fractions made from cereal grasses (typically rye, corn, and timothy). It is produced without chemical solvents and has been studied primarily for urinary and pelvic symptoms—most notably chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS), benign prostatic hyperplasia (BPH)–related lower urinary tract symptoms (LUTS), and, more recently, urinary incontinence...

Grape seed extract: Vascular health benefits, how it works, dosage range, and safety

Grape seed extract (GSE) concentrates bioactive polyphenols—especially oligomeric proanthocyanidins (OPCs)—from the tiny seeds of Vitis vinifera. These compounds act as potent antioxidants and appear to support vascular health by improving endothelial function, assisting healthy blood pressure in certain groups, and reducing leg heaviness and swelling in venous problems. Research also explores GSE for lipid balance and oxidative stress, though...

Grape seed oil: Health benefits, how to use it in cooking and skincare, dosage guidance, and safety

Grape seed oil turns a wine-making by-product into a versatile kitchen and skincare staple. Pressed from Vitis vinifera seeds, it’s naturally rich in polyunsaturated fat—primarily linoleic acid (omega-6)—with smaller amounts of oleic acid (omega-9). In the “unsaponifiable” fraction you’ll find tocopherols (vitamin E family) and phytosterols that contribute to antioxidant behavior and skin-barrier support. Refined versions offer a neutral...

Grape skin extract: Antioxidant and vascular support, evidence-based uses, dosage, and side effects

Grape skin extract concentrates the purple-red pigments and protective compounds found in the skins of Vitis vinifera grapes. These include anthocyanins, resveratrol, flavonols, and phenolic acids—molecules studied for vascular support, antioxidant action, and cellular signaling. In supplements, grape skin extract is positioned for heart and metabolic health, healthy blood vessel function, brain performance under stress, and recovery from oxidative...

Grapefruit seed extract: Antimicrobial properties, how to use it, recommended dosage, and side effects

Grapefruit seed extract (often abbreviated GSE) is a citrus-derived supplement promoted for broad antimicrobial and antioxidant support. Manufacturers typically concentrate compounds from the seeds, pulp, and white membranes, then deliver them as liquid drops, capsules, or topical sprays. People reach for GSE to help with skin breakouts, oral and throat hygiene, travelers’ tummy troubles, or to preserve homemade cosmetics....

Grapefruit seed oil: Skin and hair benefits, how to use it, recommended topical dosage, and safety

Grapefruit seed oil is a fixed, non-volatile oil pressed from the seeds of the grapefruit (Citrus paradisi). Lightweight and fast-absorbing, it’s prized for a high proportion of unsaturated fatty acids that help soften skin and smooth hair without a heavy feel. You’ll see it in face oils, serums, body lotions, and hair products where it supports the skin barrier,...

Gravel root: Uses for Urinary Health, Potential Benefits, Recommended Dosage, and Side Effects

Gravel root—also known as Joe-Pye root (Eutrochium purpureum, formerly Eupatorium purpureum)—is a North American herb with a long history in folk medicine for “kidney gravel,” or urinary stones. Today, interest centers on two realities: first, laboratory work suggests this plant contains constituents with anti-inflammatory activity; second, gravel root and related species can contain 1,2-unsaturated pyrrolizidine alkaloids (PAs), natural toxins...

Graviola extract: Benefits for Wellness, Best Forms, Dosage Ranges, and Side Effects

Graviola (Annona muricata), also called soursop or guanábana, is a tropical tree whose leaves, fruit, and seeds have long been used in folk medicine. Modern supplements typically focus on leaf extract and promise wide-ranging benefits—from immune and antioxidant support to balanced inflammation and glucose control. Laboratory research has identified unique compounds called acetogenins alongside alkaloids and polyphenols that may...

Greater bindweed: Potential Benefits and Risks, How It Works, Dosage Questions, and Interactions

Greater bindweed (Calystegia sepium), also called hedge bindweed, is a vigorous climbing plant in the morning glory family. Although best known as a hedgerow weed, it contains distinctive plant compounds—most notably calystegines (a class of nortropane alkaloids) and resin glycosides—that have drawn scientific interest. Traditional use has centered on mild laxative and topical applications, while modern lab studies on...

Greek sage: What It Is, Science-Backed Benefits, How to Take It, and Who Should Avoid It

Greek sage (Salvia fruticosa), sometimes called Greek sage tea or Cretan sage, is a Mediterranean shrub prized for its aromatic leaves and essential oil. Traditionally sipped as a digestive and soothing tea, it’s now studied for antioxidant activity, enzyme-modulating effects relevant to memory and metabolic health, and broad antimicrobial properties. Greek sage isn’t a cure-all, but it’s a versatile...

Green algae: Nutrition Facts, Research-Backed Benefits, Dosage, and Safety Tips

Green algae are a diverse group of freshwater and marine plants that have become popular as nutrient-dense supplements. Most products on shelves come from microalgae such as chlorella and some edible seaweeds like sea lettuce (Ulva). They provide concentrated protein, chlorophyll, carotenoids (lutein, zeaxanthin, beta-carotene), minerals, and unique polysaccharides. People reach for green algae to support general nutrition, antioxidant...

Green banana flour: Metabolic health benefits, dosage timing, culinary uses, and safety

Green banana flour (GBF) turns unripe bananas—naturally high in resistant starch—into a fine powder you can add to everyday foods. People use it to support healthy blood sugar, digestion, and weight management, and as a gluten-free baking option that performs surprisingly well. Because it is milled from unripe bananas, it contains less sugar and more fermentable fiber than ripe...

Green coffee bean extract: Benefits for Metabolism, Proper Use, Dosage Timing, and Safety Tips

Green coffee bean extract (GCBE) is a concentrated source of chlorogenic acids—polyphenols found in raw, unroasted coffee beans—often standardized and sold as capsules or powders. People reach for it to support healthy blood pressure, modest weight management, better fasting glucose, and overall cardiometabolic health. Unlike roasted coffee, GCBE is typically lower in caffeine (especially if decaffeinated), while preserving compounds...

Green oat extract: Cognitive benefits, how to use it, optimal dosage, and safety

Green oat extract—made from the aerial parts of Avena sativa harvested at the “milky” green stage—has gained attention as a gentle nootropic and well-being supplement. Early research suggests it may sharpen mental processing, support attention during demanding tasks, and help the body cope with stress. Because green oats are rich in distinctive compounds (including avenanthramides and specific flavonoids), they’re...

Green propolis: Benefits for Immunity and Inflammation, Dosage Ranges, and Who Should Avoid It

Green propolis is a plant–bee compound prized for its concentrated polyphenols—especially artepillin C—sourced mainly from the Brazilian shrub Baccharis dracunculifolia. Unlike honey, it is harvested as a resin and standardized into capsules, tinctures, or sprays. People turn to green propolis for immune support, oral and respiratory wellness, and its anti-inflammatory potential. In recent human studies, standardized green propolis has...

Green tea extract: Weight Management, Heart Health, Blood Sugar, and Safe Dosage

Green tea extract condenses the leaf’s most studied compounds—catechins like EGCG (epigallocatechin gallate), plus caffeine and L-theanine—into capsules, powders, or liquids. People use it to support body composition, cholesterol and triglycerides, blood pressure, and glucose control, and to add a gentle focus lift without the edginess of strong stimulants. Because extracts deliver far more catechins per dose than a...

Green-lipped mussel extract: What It Is, Proven Uses, Daily Dosage, and Side Effects

Green-lipped mussel extract (GLME) comes from Perna canaliculus, a shellfish native to New Zealand’s clean coastal waters. Unlike generic “fish oils,” GLME concentrates rare marine fatty acids (including eicosatetraenoic acid, ETA), omega-3s (EPA, DHA), sterols, and minor lipids that act on inflammatory pathways such as 5-LOX and COX. People most often use it for joint comfort and mobility in...

Griffonia simplicifolia seed extract: Evidence-Based Benefits, How to Use It, Dosage, and Safety

Griffonia simplicifolia seed extract is the primary natural source of 5-hydroxytryptophan (5-HTP)—the direct precursor to serotonin, which also converts to melatonin. Because serotonin influences mood, appetite, pain perception, and sleep, 5-HTP from Griffonia has become a popular supplement for healthy mood balance, better sleep quality, supporting migraine prevention, and easing fibromyalgia symptoms. Evidence ranges from preliminary to moderate depending...