CYP2D6 and CYP2C19 Antidepressant Pharmacogenetic Test: SSRI Response and Results
A CYP2D6 and CYP2C19 antidepressant pharmacogenetic test estimates how quickly a person may process selected antidepressants. It can help explain unusually high exposure, early...
CYP2D6 Genetic Test: Drug Metabolism, Poor Metabolizer, and Results
A CYP2D6 genetic test predicts how much functional CYP2D6 enzyme a person is likely to produce. This enzyme affects many antidepressants, opioids, antipsychotics, attention-deficit...
CYP2D6 Opioid Pharmacogenetic Test: Codeine, Tramadol, Oxycodone, and Results
A CYP2D6 opioid pharmacogenetic test predicts how efficiently the body converts certain opioids into more active metabolites. The result is most clinically useful for...
CYP3A4 Genetic Test: Drug Metabolism, Variants, and Results
A CYP3A4 genetic test looks for inherited variants that may change the activity of CYP3A4, a liver and intestinal enzyme involved in processing many...
CYP3A5 Genetic Test: Tacrolimus Dosing, Metabolism, and Results
A CYP3A5 genetic test predicts how strongly a person expresses the CYP3A5 enzyme, one of the main pathways that clears tacrolimus. People who express...
DPYD Genetic Test: Fluoropyrimidine Toxicity, 5-FU, Capecitabine, and Results
A DPYD genetic test identifies inherited variants that can reduce dihydropyrimidine dehydrogenase, or DPD, the main enzyme that breaks down fluorouracil. Reduced DPD activity...
Fluoropyrimidine Pharmacogenetic Test: DPYD, 5-FU, Capecitabine Toxicity, and Results
A fluoropyrimidine pharmacogenetic test is a pre-treatment safety assessment for people who may receive intravenous 5-fluorouracil or oral capecitabine. It usually examines DPYD, the...
G6PD Genetic Test: Medication Hemolysis Risk, Deficiency, and Results
A G6PD genetic test looks for inherited changes in the glucose-6-phosphate dehydrogenase gene that can make red blood cells unusually vulnerable to oxidative stress....
HLA-A*31:01 Genetic Test: Carbamazepine Hypersensitivity Risk and Results
An HLA-A31:01 genetic test estimates whether a person has a higher-than-average risk of immune-mediated hypersensitivity from carbamazepine. The allele is associated with several reaction...
HLA-B*15:02 Genetic Test: Carbamazepine Skin Reaction Risk and Results
The HLA-B15:02 genetic test is used to reduce the risk of Stevens–Johnson syndrome and toxic epidermal necrolysis before carbamazepine or certain related antiseizure medicines...
HLA-B*57:01 Genetic Test: Abacavir Hypersensitivity Risk and Results
The HLA-B57:01 genetic test is a standard safety check before abacavir is used to treat HIV. Abacavir can cause a serious, sometimes fatal, multisystem...
HTR2A Genetic Test: Antidepressant Response, Side Effects, and Results
An HTR2A genetic test examines variants in the gene for the serotonin 2A receptor, a brain signaling protein involved in mood, cognition, sleep, and...
IFNL3 Genetic Test: Hepatitis C Treatment Response and Results
An IFNL3 genetic test looks for inherited variants that once helped predict how likely a person with hepatitis C was to respond to interferon-based...
NAT2 Genetic Test: Isoniazid Metabolism, Slow Acetylator Status, and Results
A NAT2 genetic test estimates how quickly a person is likely to acetylate isoniazid, an important medicine used in treatment regimens for tuberculosis disease...
NUDT15 Genetic Test: Thiopurine Toxicity, Leukopenia Risk, and Results
A NUDT15 genetic test helps estimate whether standard doses of thiopurine medicines could cause excessive bone marrow suppression. Thiopurines—including mercaptopurine, azathioprine, and thioguanine—are used...
OPRM1 Genetic Test: Opioid Response, Pain Treatment, and Results
An OPRM1 genetic test looks for inherited variation in the gene that makes the mu-opioid receptor, a major target of medicines such as morphine,...
Pain Medication Pharmacogenetic Test: Opioids, CYP2D6, OPRM1, and Results
A pain medication pharmacogenetic test looks for inherited gene variants that may change how a person processes or responds to certain analgesics. The clearest...
Pharmacogenetic Panel Test: Medication Response, Gene Variants, and Results
A pharmacogenetic panel test examines several inherited genes at once to identify medication responses that may differ from the average. It can reveal slower...
Psychiatric Pharmacogenetic Test: Antidepressants, Antipsychotics, Genes, and Results
A psychiatric pharmacogenetic test analyzes inherited gene variants that may affect the metabolism, exposure, or tolerability of selected antidepressants and antipsychotics. The strongest prescribing...
RYR1 Genetic Test: Malignant Hyperthermia Risk and Anesthesia Results
An RYR1 genetic test looks for inherited variants associated with malignant hyperthermia susceptibility, a potentially fatal reaction to certain general anesthetics and the muscle...