Evidence-Based Supplement & Herb Guides

Ixora alba: Wound Healing and Antimicrobial Properties, Practical Dosage, and Side Effects

Ixora alba—often called white ixora—is a compact, evergreen shrub in the coffee family (Rubiaceae) known for starry, ivory flower clusters and a long record...

Ixora chinensis: Antioxidant and Anti-Inflammatory Actions, Best Preparations, Dosage, and Safety

Ixora chinensis—sometimes called Chinese ixora or jungle geranium—is a tropical evergreen shrub in the coffee family (Rubiaceae). Beyond its ornamental value, different parts of...

Ixora coccinea: Wound Healing Benefits, Antimicrobial Properties, How to Use, and Side Effects

Ixora coccinea—also called jungle geranium, flame of the woods, or red ixora—is a tropical shrub prized for its bright clusters of flowers and a...

Izba eye drops: benefits for glaucoma, how it works, recommended dosage, and safety

Izba is a prescription eye drop used to lower high pressure inside the eye (intraocular pressure, IOP) in people with open-angle glaucoma or ocular...

Izervay benefits and risks: how it works, who should get it, dosing schedule, and side effects

Izervay is a prescription intravitreal injection used to treat geographic atrophy (GA), the advanced form of dry age-related macular degeneration. It contains avacincaptad pegol,...

Izumio benefits: hydrogen water science, real-world uses, dosage, and safety explained

Izumio is a branded form of hydrogen-rich water (HRW)—plain water infused with dissolved molecular hydrogen gas (H₂). Fans point to H₂’s selective antioxidant and...

Acetyl L Carnitine for Aging: Mitochondrial Function and Cognition

Acetyl L carnitine may support mitochondrial function, mental energy, and mild cognitive concerns in selected adults, but dosing, safety, and tracking matter.

Acetyl L carnitine, often shortened to ALCAR or ALC, is a carnitine form used in supplements for brain energy, nerve function, fatigue, and age-related...

Aged Garlic Extract for Longevity: Cardiovascular and Immune Support

Learn how aged garlic extract supports cardiovascular aging, blood pressure, immune resilience, dosing, safety, and smart tracking for a longevity-focused supplement plan.

Aged garlic extract is one of the better-studied garlic supplements for healthy aging because it targets two systems that shape healthspan: blood vessels and...

Akkermansia Supplements and Aging: What Supplementation Can and Cannot Do

Akkermansia supplements show early promise for insulin sensitivity, weight maintenance, gut barrier support, and muscle function, but they do not reverse aging or replace core healthspan habits.

Akkermansia muciniphila has moved from a little-known gut bacterium to one of the most discussed “next-generation probiotics.” Interest is high because higher levels of...

Alpha Ketoglutarate for Aging: Where the Science Stands

Alpha ketoglutarate for aging has promising biology but limited human proof. Learn what AKG does, what studies show, how Ca-AKG differs, and what safety cautions matter.

Alpha ketoglutarate, often shortened to AKG or α-ketoglutarate, sits at an unusual crossroads in longevity research. It is not a rare plant extract or...

Alpha Lipoic Acid for Healthy Aging: Insulin Sensitivity and Mitochondria

Alpha lipoic acid may support insulin sensitivity, glucose control, and redox balance in healthy aging. Learn benefits, dosing, safety, and how to track results.

Alpha lipoic acid is a sulfur-containing compound that sits at the crossroads of energy metabolism, antioxidant defense, and glucose control. The body makes small...

Apigenin and Luteolin for Healthy Aging: Flavones with Potential

Apigenin and luteolin are plant flavones linked to inflammation, sleep, senescence, and cellular stress pathways. Learn food sources, supplement cautions, dosing context, and safety tips for healthy aging.

Apigenin and luteolin are plant flavones found in herbs, vegetables, teas, and some supplements. They attract attention in healthy aging because they interact with...

Ashwagandha for Healthy Aging: Sleep, Stress, and Cortisol

Ashwagandha may support healthy aging by improving stress, sleep quality, and cortisol patterns, but benefits depend on dose, product quality, safety, and the broader recovery plan.

Ashwagandha is best understood as a stress-and-sleep supplement, not a proven life-extension compound. Human trials suggest that some standardized extracts of Withania somnifera reduce...

Astaxanthin for Aging: Skin, Eyes, and Oxidative Stress

Astaxanthin for aging may support skin hydration, eye comfort, and oxidative stress balance. Learn benefits, dosing, safety, and realistic expectations.

Astaxanthin is a red-orange carotenoid found in microalgae, salmon, trout, shrimp, krill, and some dietary supplements. It attracts attention in healthy aging because it...

B Vitamins for Aging: B12, Folate, and B6 for Homocysteine

Learn how vitamin B12, folate, and B6 affect homocysteine in aging, when to test, which supplement forms and doses make sense, and how to avoid safety mistakes.

Homocysteine is a normal amino acid byproduct, but it becomes more useful as a health clue when it stays elevated. Vitamin B12, folate, and...

Beetroot and Nitrate Supplements for Longevity: Vascular Function and Exercise Capacity

Beetroot and nitrate supplements may support vascular function, blood pressure, and exercise capacity through nitric oxide. Learn dosing, timing, benefits, and safety.

Beetroot and nitrate supplements support healthy aging mainly by increasing nitric oxide, a short-lived signaling molecule that helps blood vessels relax, improves blood flow,...

Berberine for Healthy Aging: Glucose, Lipids, and AMPK

Berberine may support healthy aging by improving glucose, insulin resistance, lipids, and AMPK signaling. Learn who benefits, how to dose it, and when to avoid it.

Berberine is a plant-derived compound with the strongest supplement evidence in cardiometabolic health: blood glucose, insulin resistance, triglycerides, LDL cholesterol, and fatty liver markers....

Beta Alanine and Carnosine for Healthy Aging: Performance and Fatigue

Beta alanine raises muscle carnosine and may help healthy adults reduce high-intensity muscle fatigue, improve interval tolerance, and support training quality with safe dosing.

Beta alanine is best known as a sports supplement, but its most interesting use in healthy aging is more specific: it helps muscle cells...

Betaine TMG for Longevity: Methylation and Homocysteine

Betaine TMG supports homocysteine metabolism through methylation, but it is not a proven longevity pill. Learn who may benefit, what dose to consider, and which labs to monitor.

Betaine, also called trimethylglycine or TMG, sits at the crossroads of nutrition, methylation, liver metabolism, and homocysteine control. It is not a proven longevity...

Boswellia for Healthy Aging: Joint Comfort Without Reliance on NSAIDs

Boswellia may support knee osteoarthritis comfort and mobility while reducing reliance on frequent NSAID use. Learn evidence, dosing, safety, and how to choose a quality supplement.

Boswellia is best understood as a joint-comfort supplement, not a painkiller replacement. Extracts from the resin of Boswellia serrata, also called Indian frankincense, contain...