Latest

Learn how lung cancer MRD ctDNA testing detects molecular residual disease, what positive and negative results mean, how it can precede recurrence on scans, and why treatment decisions still require clinical context.

Minimal Residual Disease ctDNA Test for Lung Cancer: Recurrence Monitoring, MRD, and Tumor DNA

Learn what MSI testing means in lung cancer, how MSI-H, MSS, dMMR, and pMMR results differ, how NGS, PCR, and IHC are used, and why this rare biomarker can matter for immunotherapy and hereditary evaluation.

MSI Test for Lung Cancer: Microsatellite Instability, Mismatch Repair, and Result Meaning

Learn how Napsin A IHC supports lung adenocarcinoma diagnosis, what positive granular cytoplasmic staining means, why negative results do not exclude lung cancer, and when other tumor origins must be considered.

Napsin A IHC Test for Lung Cancer: Adenocarcinoma Marker, Tumor Origin, and Positive...

Non-Small Cell Lung Cancer Biomarker Test: Driver Mutations, PD-L1, and Molecular Profile

Learn what an NSE blood test means in small cell lung cancer, why levels can be high, how hemolysis causes false elevations, and how serial NSE trends may support treatment and recurrence monitoring.

NSE Test for Lung Cancer: Small Cell Lung Cancer Marker, High Levels, and...

Understand NTRK fusion testing in lung cancer, including tumor-agnostic meaning, RNA NGS, pan-TRK IHC, positive results, negative-result limits, and next steps.

NTRK Fusion Test for Lung Cancer: Gene Fusion, Tumor-Agnostic Marker, and Molecular Meaning

Diagnostics

Home Diagnostics Page 8

Learn what an ESR1 mutation test means in breast cancer, how ctDNA testing detects hormone resistance, how results affect treatment, and how ESR1 relates to recurrence.

ESR1 Mutation Test: Breast Cancer, Hormone Resistance Marker, Mutation Status, and...

EWSR1 Fusion Test Sarcoma, Ewing Tumor, Gene Fusion, and Tumor Classification

EWSR1 Fusion Test: Sarcoma, Ewing Tumor, Gene Fusion, and Tumor Classification

Learn what an EZH2 mutation test means in follicular lymphoma, how positive and negative results are interpreted, and how the 2026 tazemetostat withdrawal changes treatment relevance.

EZH2 Mutation Test: Lymphoma, Mutation Status, Prognosis, and Molecular Meaning

Learn what an FGFR3 mutation test means in bladder cancer, which FGFR3 alterations are actionable, how tissue and ctDNA testing work, and how results can guide treatment.

FGFR3 Mutation Test: Bladder Cancer, Mutation Status, and Molecular Meaning

Learn what a FUS fusion test detects in sarcoma, what FUS::DDIT3 and FUS::CREB3L2 mean, how testing is performed, and how results guide tumor classification.

FUS Fusion Test: Sarcoma Gene Fusion, Tumor Classification, and Molecular Result

Learn how a gene fusion panel detects cancer rearrangements, why RNA-based NGS is useful, what positive and negative results mean, and how fusions can guide tumor classification and targeted therapy.

Gene Fusion Panel Test: Cancer Fusions, Rearrangement Markers, and Molecular Tumor...

Learn what a HER2/ERBB2 mutation test means in lung, breast, and gastric cancer, how mutations differ from HER2 amplification or IHC, and how results can guide targeted treatment.

HER2/ERBB2 Mutation Test: Breast, Gastric, Lung Cancer, Mutation Status, and HER2...

Learn what an HRD test measures in ovarian cancer, how genomic instability scores and BRCA status are interpreted, what HRD-positive means, and how results can inform PARP inhibitor treatment decisions.

Homologous Recombination Deficiency (HRD) Test: DNA Repair Deficiency, Ovarian Cancer, and...

Learn what an HRAS mutation test means in head and neck cancer and thyroid disease, how hotspot and VAF results are interpreted, and why a positive HRAS result has different implications by tumor type.

HRAS Mutation Test: Head and Neck Cancer, Thyroid Cancer, Mutation Status,...

Learn what an IDH1 mutation test means in glioma, AML, and cholangiocarcinoma, how R132 mutations are detected, and how positive results can affect diagnosis and targeted treatment.

IDH1 Mutation Test: Glioma, Leukemia, Cholangiocarcinoma, Mutation Status, and Meaning

Understand what an IDH2 mutation test means in AML, glioma, and cholangiocarcinoma, including positive and negative results, treatment relevance, testing methods, and important limitations.

IDH2 Mutation Test: Leukemia, Glioma, Cholangiocarcinoma, Mutation Status, and Meaning

Learn what a KIT mutation test means in GIST, melanoma, and mast cell disease, including exon-specific results, KIT D816V, treatment relevance, CD117 differences, and testing limitations.

KIT Mutation Test: GIST, Melanoma, Mast Cell Disease, Mutation Status, and...

Understand KRAS mutation test results in colon, lung, and pancreatic cancer, including G12C, G12D, treatment resistance, targeted therapy, negative results, and testing limits.

KRAS Mutation Test: Colon, Lung, Pancreatic Cancer, Mutation Status, and Result...

Understand MDM2 amplification testing for liposarcoma, including FISH ratios, copy number gain, polysomy, positive and negative results, diagnostic pitfalls, and next steps.

MDM2 Amplification Test: Liposarcoma, Copy Number Gain, Tumor Diagnosis, and FISH...

Understand MET amplification test results in lung and gastric cancer, including FISH ratios, NGS copy number, polysomy, high-level amplification, resistance, and treatment implications.

MET Amplification Test: Lung Cancer, Gastric Cancer, Copy Number Gain, and...

Understand MSI test results for Lynch syndrome and cancer care, including MSI-H, MSS, mismatch repair deficiency, immunotherapy relevance, hereditary follow-up, discordant results, and next steps.

Microsatellite Instability (MSI) Test: Lynch Syndrome, Mismatch Repair, Cancer Risk, and...

Understand MMR gene testing for MLH1, MSH2, MSH6, PMS2, EPCAM, and Lynch syndrome, including IHC patterns, MSI, germline results, cancer risk, and next steps.

Mismatch Repair (MMR) Gene Test: MLH1, MSH2, MSH6, PMS2, and Lynch...

Understand MLH1 mutation testing for Lynch syndrome and colon cancer, including MLH1/PMS2 loss, promoter methylation, BRAF triage, germline variants, cancer risk, and result meaning.

MLH1 Mutation Test: Lynch Syndrome, Colon Cancer, Mismatch Repair, and Variant...

Understand MPL mutation test results in thrombocytosis and myeloproliferative neoplasms, including W515 variants, ET versus myelofibrosis, negative results, VAF, prognosis, and next steps.

MPL Mutation Test: Myeloproliferative Neoplasm, Platelets, Thrombocytosis, and Result Meaning

Understand MSH2 mutation testing for Lynch syndrome, including MSH2/MSH6 loss, EPCAM deletions, germline results, colorectal and urinary-tract cancer risk, MSI, and next steps.

MSH2 Mutation Test: Lynch Syndrome, Colon Cancer, Mismatch Repair, and Variant...

1...789...92 Page 8 of 92